The Substance 2024 Release Date Trailer. 'the substance,' starring demi moore as a fading celebrity who takes a black market drug to reverse her age, has unveiled its first trailer. After enjoying its world premiere at cannes on may 19, the substance will arrive in u.s.

Mubi has released the substance trailer for its upcoming body horror thriller, starring golden globe nominees demi moore and margaret qualley. The substance streaming release date.